Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity

doi:10.3390/md16090291

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	Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity
	Jin, Weihua 1; Ren, Langlang 1; Liu, Bing 1; Zhang, Quanbin 2,3; Zhong, Weihong 1
	2018-09-01
发表期刊	MARINE DRUGS
ISSN	1660-3397
卷号	16 期号:9 页码:12
通讯作者	Zhang, Quanbin([email protected]) ; Zhong, Weihong([email protected])
摘要	Glucuronomannan oligosaccharides (Gs) were derived from fucoidan, which was extracted from the brown alga Sargassum thunbergii. Sulfated glucuronomannan oligosaccharides (SGs) were obtained by the sulfation of Gs. NMR techniques were used to reveal that the order of sulfation was Man-C6 > Man-C4 > Man-C1R > GlcA-C3 > Man-C3 > GlcA-C2. Finally, the antioxidant activities (hydroxyl radical scavenging activity, superoxide radical scavenging activity, reducing power and DPPH radical scavenging activity) of Gs and SGs were determined. The findings showed that the higher the degree of polymerization, the better the activity, except for the hydroxyl radical scavenging activity. In addition, the higher the sulfate content, the lower the activities for the reducing power and DPPH radical scavenging activity. Opposite results were found for the superoxide radical scavenging activity. Finally, compared with fucoidan, most Gs and SGs had higher antioxidant activity, suggesting that they might be good candidates for antioxidants.
关键词	glucuronomannan oligosaccharides sulfation antioxidant activity
DOI	10.3390/md16090291
收录类别	SCI
语种	英语
WOS研究方向	Pharmacology & Pharmacy
WOS类目	Chemistry, Medicinal
WOS记录号	WOS:000445636600002
出版者	MDPI
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/160386
专题	实验海洋生物学重点实验室
通讯作者	Zhang, Quanbin; Zhong, Weihong
作者单位	1.Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Hangzhou 310023, Zhejiang, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266000, Peoples R China
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Jin, Weihua,Ren, Langlang,Liu, Bing,et al. Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity[J]. MARINE DRUGS,2018,16(9):12.
APA	Jin, Weihua,Ren, Langlang,Liu, Bing,Zhang, Quanbin,&Zhong, Weihong.(2018).Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity.MARINE DRUGS,16(9),12.
MLA	Jin, Weihua,et al."Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity".MARINE DRUGS 16.9(2018):12.

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