Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups

doi:10.1016/j.ijbiomac.2018.03.179

IOCAS-IR > 实验海洋生物学重点实验室

	Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups
	Liu, Weixiang 1,2,3,4; Qin, Yukun1,2,3 ; Liu, Song 1,2,3; Xing, Ronge1,2,3 ; Yu, Huahua1,2,3 ; Chen, Xiaolin 1,2,3; Li, Kecheng 1,2,3; Li, Pengcheng1,2,3
	2018-07-15
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN	0141-8130
卷号	114 页码:942-949
通讯作者	Qin, Yukun([email protected]) ; Li, Pengcheng([email protected])
摘要	A novel type of water soluble chitosan derivatives (TQCSPX) were synthesized including 3-aminopyridine (TQCSPI) and 3-Amino-4-methylpyridine (TQCSP2). The theoretical structures of TQCSPX were calculated by Gaussian 09 and confirmed by FT-IR, H-1 NMR, C-13 NMR, elemental analysis and XRD. The antifungal properties of TQCSPX against Phytophthora capsici (P. capsici), Rhizoctonia solani (R. solani), Fusarium oxysporum (F. oxysporum) and Fusarium solani (F. solani) were evaluated at concentrations ranging from 0.2 mg/mL to 0.8 mg/mL Antifungal results indicated that the derivatives have significantly enhanced antifungal activity after quaternized compared with the original chitosan (CS). Moreover, TQCSPI inhibited the growth of P. capsici with inhibitory indices of 91.94% at 0.8 mg/mL The experimental results demonstrated that the increasing number of the positive charge would improve the antifungal efficiency of chitosan, which may provide a novel direction for the development of fungicides. (C) 2018 Elsevier B.V. All rights reserved.
关键词	Quaternized chitosan Aminopyridine Antifungal
DOI	10.1016/j.ijbiomac.2018.03.179
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41306071]###1538; Scientific and Technological Innovation Project - Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02]###218; Science and Technology Program - Qingdao[17-3-3-60-nsh]###1975; National Natural Science Foundation of China[41306071]; Scientific and Technological Innovation Project - Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02]; Science and Technology Program - Qingdao[17-3-3-60-nsh]
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science
WOS记录号	WOS:000435056900108
出版者	ELSEVIER SCIENCE BV
引用统计	被引频次：52[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/159407
专题	实验海洋生物学重点实验室
通讯作者	Qin, Yukun; Li, Pengcheng
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
第一作者单位	中国科学院海洋研究所
通讯作者单位	中国科学院海洋研究所
推荐引用方式 GB/T 7714	Liu, Weixiang,Qin, Yukun,Liu, Song,et al. Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,114:942-949.
APA	Liu, Weixiang.,Qin, Yukun.,Liu, Song.,Xing, Ronge.,Yu, Huahua.,...&Li, Pengcheng.(2018).Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,114,942-949.
MLA	Liu, Weixiang,et al."Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 114(2018):942-949.

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