Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii | |
Wang, Jun-Feng1,2; Liang, Rui3; Liao, Sheng-Rong1; Yang, Bin1; Tu, Zheng-Chao3; Lin, Xiu-Ping1; Wang, Bin-Gui2 ; Liu, Yonghong1,4,5
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| 2017-07-01 | |
| 发表期刊 | FITOTERAPIA
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| 卷号 | 120页码:164-170 |
| 文章类型 | Article |
| 摘要 | Ten new salicyloid derivatives, namely vaccinols J-S (1-10), along with five known compounds (11-15) were isolated from Pestalotiopsis vaccinii (cgmcc3.9199) endogenous with the mangrove plant Kandelia candel (L.) Druce (Rhizophoraceae). Their structures including absolute configurations were established on the basis of spectroscopic analysis, optical rotation, CD spectra, quantum ECD calculations. To the best of our knowledge, vaccinol J (1) is the first example of salicyloid derivatives containing 2-methylfuran moiety. All of the new compounds were tested for their anti-enterovirus 71 (EV71) and cytotoxic activities. Among them, vaccinol J (1) exhibited in vitro anti-EV71 with IC50 value of 30.7 mu M (IC50 177.0 mu M for the positive control ribavirin). |
| 关键词 | Endophytic Fungus Pestalotiopsis Vaccinii Salicyloid Anti-enterovirus 71 Activity |
| DOI | 10.1016/j.fitote.2017.06.013 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000407404000024 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 版本 | 出版稿 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/143098 |
| 专题 | 实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, South China Sea Inst Oceanol,RNAM Ctr Marine Micr, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Guangdong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510530, Guangdong, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.South China Sea Bioresource Exploitat & Utilizat, Guangzhou, Guangdong, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所; 实验海洋生物学重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang, Jun-Feng,Liang, Rui,Liao, Sheng-Rong,et al. Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii[J]. FITOTERAPIA,2017,120:164-170. |
| APA | Wang, Jun-Feng.,Liang, Rui.,Liao, Sheng-Rong.,Yang, Bin.,Tu, Zheng-Chao.,...&Liu, Yonghong.(2017).Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii.FITOTERAPIA,120,164-170. |
| MLA | Wang, Jun-Feng,et al."Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii".FITOTERAPIA 120(2017):164-170. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Vaccinols J-S, ten n（669KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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