| Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review | |
| Wang, Bao-Cheng1,2; Wang, Li-Jun1; Jiang, Bo1; Wang, Shuai-Yu1; Wu, Ning1; Li, Xiang-Qian1; Shi, Da-Yong1,2,3 | |
| 2017 | |
| 发表期刊 | MINI-REVIEWS IN MEDICINAL CHEMISTRY
 |
| 卷号 | 17期号:8页码:683-692 |
| 文章类型 | Review |
| 摘要 | Background: The widespread application of fluorine in drug design benefits from distinctive properties. Incorporation of fluorine can positively modulate certain pharmacokinetics properties, including lipophilicity, eletrophilicity, metabolic stability, chemical stability, et al., which were of interest to medicinal chemists. Herein, fluorinated compounds, which have been designed and evaluated for anticancer, antimicrobial, anti-inflammatory and antivirus activity, et al. during the last 6 years (2010-2015) are summarized. |
| 关键词 | Application Of Fluorine Anticancer Antimicrobial Anti-inflammatory Antivirus Activity Drug Design Importance Of Fluorinated Compounds |
| DOI | 10.2174/1389557515666151016124957 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000402475700005 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 版本 | 出版稿 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/137080 |
| 专题 | 海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, Qingdao 266071, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Bao-Cheng,Wang, Li-Jun,Jiang, Bo,et al. Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2017,17(8):683-692. |
| APA | Wang, Bao-Cheng.,Wang, Li-Jun.,Jiang, Bo.,Wang, Shuai-Yu.,Wu, Ning.,...&Shi, Da-Yong.(2017).Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review.MINI-REVIEWS IN MEDICINAL CHEMISTRY,17(8),683-692. |
| MLA | Wang, Bao-Cheng,et al."Application of Fluorine in Drug Design During 2010-2015 Years: A Mini-Review".MINI-REVIEWS IN MEDICINAL CHEMISTRY 17.8(2017):683-692. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Application of Fluor（1080KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 浏览 | |
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