Institutional Repository of Key Laboratory of Marine Environmental Corrosion and Bio-fouling, IOCAS
| Controlled drug release characteristics and enhanced antibacterial effect of graphene oxide-drug intercalated layered double hydroxide hybrid films | |
Wang, Yi1 ; Zhang, Dun1; Bao, Qi1,2; Wu, Jiajia1,2; Wan, Yi1,2; Zhang, D (reprint author), Chinese Acad Sci, Natl Engn Res Ctr Marine Corros Protect, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China.
| |
| 2012-11-21 | |
| 发表期刊 | JOURNAL OF MATERIALS CHEMISTRY
 |
| ISSN | 0959-9428 |
| 卷号 | 22期号:43页码:23106-23113 |
| 文章类型 | Article |
| 摘要 | Novel graphene oxide-benzylpenicillin (BP) anion intercalated Mg-Al layered double hydroxide (GO-BP-LDH) hybrid films were prepared via a simple solvent evaporation process. The release behaviour of BP anions and the antibacterial activity have also been investigated. The release time can be tailored by adjusting the film composition and increased by decreasing the GO/BP-LDH mass ratio. By applying release kinetic models to the drug release processes, the mechanism of release of BP anions from the GO-BP-LDH hybrid film was found to follow the first-order model. In addition, the hybrid film exhibited an enhanced synergistic antibacterial effect compared with the single GO film, which can be attributed to the combination of the antibacterial activity of GO and BP anions released from the hybrid film system. |
| 关键词 | In-vitro Release Composites Nanosheets Electrode Supercapacitor Transparent Fabrication Hydrogels Kinetics Bacteria |
| 学科领域 | Chemistry, Physical ; Materials Science, Multidisciplinary |
| DOI | 10.1039/c2jm35144g |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000310721400039 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12461 |
| 专题 | 海洋环境腐蚀与生物污损重点实验室 |
| 通讯作者 | Zhang, D (reprint author), Chinese Acad Sci, Natl Engn Res Ctr Marine Corros Protect, Inst Oceanol, 7 Nanhai Rd, Qingdao 266071, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Natl Engn Res Ctr Marine Corros Protect, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Yi,Zhang, Dun,Bao, Qi,et al. Controlled drug release characteristics and enhanced antibacterial effect of graphene oxide-drug intercalated layered double hydroxide hybrid films[J]. JOURNAL OF MATERIALS CHEMISTRY,2012,22(43):23106-23113. |
| APA | Wang, Yi,Zhang, Dun,Bao, Qi,Wu, Jiajia,Wan, Yi,&Zhang, D .(2012).Controlled drug release characteristics and enhanced antibacterial effect of graphene oxide-drug intercalated layered double hydroxide hybrid films.JOURNAL OF MATERIALS CHEMISTRY,22(43),23106-23113. |
| MLA | Wang, Yi,et al."Controlled drug release characteristics and enhanced antibacterial effect of graphene oxide-drug intercalated layered double hydroxide hybrid films".JOURNAL OF MATERIALS CHEMISTRY 22.43(2012):23106-23113. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Controlled drug rele（900KB） | 限制开放 | 使用许可 | 浏览 | |||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论