Institutional Repository of Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
| Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48 | |
Sun, Hao-Fen2,3; Li, Xiao-Ming2; Meng, Li1; Cui, Chuan-Ming2,3; Gao, Shu-Shan2,3; Li, Chun-Shun2; Huang, Cai-Guo1; Wang, Bin-Gui2 ; Huang, CG (reprint author), Mil Med Coll 2, Dept Biochem & Mol Biol, Xiangyin Rd 800, Shanghai 200433, Peoples R China.
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| 2012-02-01 | |
| 发表期刊 | JOURNAL OF NATURAL PRODUCTS
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| ISSN | 0163-3864 |
| 卷号 | 75期号:2页码:148-152 |
| 文章类型 | Article |
| 摘要 | Bioassay-guided fractionation of the culture extract of Aspergillus wentii EN-48, an endophytic fungus isolated from an unidentified marine brown algal species of the genus Sargassum, led to the isolation of three new tetranorlabdane diterpenoids, asperolides A-C (1-3), and five related derivatives (4-8). The structures of these compounds were established on the basis of spectroscopic interpretation, and compound 1 was confirmed by X-ray crystallographic analysis. The absolute configuration of I was determined by application of the modified Mosher's method. An Xray structure for wentilactone B (6) is also reported. Compounds 1-8 were evaluated for cytotoxic and antibacterial activities. |
| 关键词 | Penicillium-chrysogenum Qen-24s Norditerpene Dilactones Chaetomium-globosum Antifungal Metabolites Ochraceus Alkaloids Chemistry Steroids Agents |
| 学科领域 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1021/np2006742 |
| URL | 查看原文 |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000300601500006 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12286 |
| 专题 | 实验海洋生物学重点实验室 |
| 通讯作者 | Huang, CG (reprint author), Mil Med Coll 2, Dept Biochem & Mol Biol, Xiangyin Rd 800, Shanghai 200433, Peoples R China. |
| 作者单位 | 1.Second Mil Med Univ, Dept Biochem & Mol Biol, Shanghai 200433, Peoples R China 2.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Sun, Hao-Fen,Li, Xiao-Ming,Meng, Li,et al. Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(2):148-152. |
| APA | Sun, Hao-Fen.,Li, Xiao-Ming.,Meng, Li.,Cui, Chuan-Ming.,Gao, Shu-Shan.,...&Huang, CG .(2012).Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48.JOURNAL OF NATURAL PRODUCTS,75(2),148-152. |
| MLA | Sun, Hao-Fen,et al."Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48".JOURNAL OF NATURAL PRODUCTS 75.2(2012):148-152. |
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| Asperolides A-C, Tet（905KB） | 限制开放 | 使用许可 | 浏览 | |||
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