| The oyster genome reveals stress adaptation and complexity of shell formation | |
Zhang, Guofan2; Fang, Xiaodong1; Guo, Ximing3; Li, Li2; Luo, Ruibang1,4; Xu, Fei2; Yang, Pengcheng1; Zhang, Linlin2; Wang, Xiaotong2; Qi, Haigang2; Xiong, Zhiqiang1; Que, Huayong2; Xie, Yinlong1,4; Holland, Peter W. H.5; Paps, Jordi5; Zhu, Yabing1; Wu, Fucun2; Chen, Yuanxin1; Wang, Jiafeng2; Peng, Chunfang1; Meng, Jie2 ; Yang, Lan1; Liu, Jun2; Wen, Bo1; Zhang, Na2; Huang, Zhiyong1; Zhu, Qihui2; Feng, Yue1; Mount, Andrew6; Hedgecock, Dennis7; Xu, Zhe8; Liu, Yunjie1; Domazet-Loso, Tomislav9; Du, Yishuai2; Sun, Xiaoqing1; Zhang, Shoudu2; Liu, Binghang1,4; Cheng, Peizhou2; Jiang, Xuanting1; Li, Juan2; Fan, Dingding1; Wang, Wei2; Fu, Wenjing1; Wang, Tong2; Wang, Bo1; Zhang, Jibiao2; Peng, Zhiyu1; Li, Yingxiang2; Li, Na1; Wang, Jinpeng2; Chen, Maoshan1; He, Yan3; Tan, Fengji1; Song, Xiaorui2; Zheng, Qiumei1; Huang, Ronglian2; Yang, Hailong1; Du, Xuedi2; Chen, Li1; Yang, Mei2; Gaffney, Patrick M.10; Wang, Shan3; Luo, Longhai1; She, Zhicai2; Ming, Yao1; Huang, Wen2; Zhang, Shu1; Huang, Baoyu2; Zhang, Yong1; Qu, Tao2; Ni, Peixiang1; Miao, Guoying2; Wang, Junyi1; Wang, Qiang2; Steinberg, Christian E. W.11; Wang, Haiyan2; Li, Ning1; Qian, Lumin3; Zhang, Guojie1; Li, Yingrui1; Yang, Huanming1; Liu, Xiao2; Wang, Jian1; Yin, Ye1; Wang, Jun1,12,13; Wang, J (reprint author), BGI Shenzhen, Shenzhen 518083, Peoples R China.
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| 2012-10-04 | |
| 发表期刊 | NATURE
 |
| ISSN | 0028-0836 |
| 卷号 | 490期号:7418页码:49-54 |
| 文章类型 | Article |
| 摘要 | The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. Transcriptome studies reveal an extensive set of genes responding to environmental stress. The expansion of genes coding for heat shock protein 70 and inhibitors of apoptosis is probably central to the oyster's adaptation to sessile life in the highly stressful intertidal zone. Our analyses also show that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes. The oyster genome sequence fills a void in our understanding of the Lophotrochozoa. |
| 关键词 | Transposable Elements Crassostrea-gigas Bivalve Mollusks Parahox Genes Proteins Sequence Evolution Discovery Apoptosis Pathway |
| 学科领域 | Multidisciplinary Sciences |
| DOI | 10.1038/nature11413 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000309446800030 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12252 |
| 专题 | 海洋生物技术研发中心 实验海洋生物学重点实验室 |
| 通讯作者 | Wang, J (reprint author), BGI Shenzhen, Shenzhen 518083, Peoples R China. |
| 作者单位 | 1.BGI Shenzhen, Shenzhen 518083, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Rutgers State Univ, Inst Marine & Coastal Sci, Haskin Shellfish Res Lab, Port Norris, NJ 08349 USA 4.HKU BGI Bioinformat Algorithms & Core Technol Res, Hong Kong, Hong Kong, Peoples R China 5.Univ Oxford, Dept Zool, Oxford OX1 3PS, England 6.Clemson Univ, Dept Biol Sci, Clemson, SC 29634 USA 7.Univ So Calif, Dept Biol Sci, Los Angeles, CA 90089 USA 8.Atlantic Cape Community Coll, Mays Landing, NJ 08330 USA 9.Rudjer Boskovic Inst, Lab Evolutionary Genet, HR-10002 Zagreb, Croatia 10.Univ Delaware, Sch Marine Sci & Policy, Lewes, DE 19958 USA 11.Humboldt Univ Berlin Arboretum, Inst Biol, D-12437 Berlin, Germany 12.Univ Copenhagen, Dept Biol, DK-2200 Copenhagen, Denmark 13.Univ Copenhagen, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2200 Copenhagen, Denmark |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Zhang, Guofan,Fang, Xiaodong,Guo, Ximing,et al. The oyster genome reveals stress adaptation and complexity of shell formation[J]. NATURE,2012,490(7418):49-54. |
| APA | Zhang, Guofan.,Fang, Xiaodong.,Guo, Ximing.,Li, Li.,Luo, Ruibang.,...&Wang, J .(2012).The oyster genome reveals stress adaptation and complexity of shell formation.NATURE,490(7418),49-54. |
| MLA | Zhang, Guofan,et al."The oyster genome reveals stress adaptation and complexity of shell formation".NATURE 490.7418(2012):49-54. |
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| The oyster genome re（712KB） | 限制开放 | 使用许可 | 浏览 | |||
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