| Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta) | |
| Qi, Huimin1,2; Huang, Liye3; Liu, Xiaolei4; Liu, Dongmei2; Zhang, Quanbin1; Liu, Shunmei2; Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China. | |
| 2012-01-15 | |
| 发表期刊 | CARBOHYDRATE POLYMERS
 |
| ISSN | 0144-8617 |
| 卷号 | 87期号:2页码:1637-1640 |
| 文章类型 | Article |
| 摘要 | In this study, high sulfate content ulvan (HU) was prepared with sulfur trioxide/N,N-dimethylformamide (SO3-DMF) in formamide, and the antihyperlipidemic activity of ulvan and HU in mice was determined. Obvious differences in antihyperlipidemic activity between natural ulvan and HU were observed, moreover, the antihyperlipidemic activity of HU-fed 250 mg/kg was the strongest, compared to natural ulvan fed group, triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) concentrations were significantly decreased 28.1% (P < 0.05) and 28.4% (P < 0.01), respectively. It was likely that the sulfate content had significant effect on the antihyperlipidemic activity. On the other hand, the results proved that the antihyperlipidemic activity was not concentration dependent for HU-fed mice. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved. |
| 关键词 | Polysaccharide Ulva Pertusa High Sulfate Content Ulvan Antihyperlipidemic Activity |
| 学科领域 | Chemistry, Applied ; Chemistry, Organic ; Polymer Science |
| DOI | 10.1016/j.carbpol.2011.09.073 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000298305400092 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/12212 |
| 专题 | 海洋生物技术研发中心 |
| 通讯作者 | Zhang, QB (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China. |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Weifang Med Univ, Weifang 261053, Peoples R China 3.Shandong Inst Sci & Tech Informat, Jinan 250101, Peoples R China 4.Weifang Univ, Weifang 261061, Peoples R China |
| 第一作者单位 | 中国科学院海洋研究所 |
| 推荐引用方式 GB/T 7714 | Qi, Huimin,Huang, Liye,Liu, Xiaolei,et al. Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta)[J]. CARBOHYDRATE POLYMERS,2012,87(2):1637-1640. |
| APA | Qi, Huimin.,Huang, Liye.,Liu, Xiaolei.,Liu, Dongmei.,Zhang, Quanbin.,...&Zhang, QB .(2012).Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta).CARBOHYDRATE POLYMERS,87(2),1637-1640. |
| MLA | Qi, Huimin,et al."Antihyperlipidemic activity of high sulfate content derivative of polysaccharide extracted from Ulva pertusa (Chlorophyta)".CARBOHYDRATE POLYMERS 87.2(2012):1637-1640. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Antihyperlipidemic a（268KB） | 限制开放 | 使用许可 | 浏览 | |||
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