Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides

doi:10.1021/jf2022447

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	Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides
	Li, Ke 1; Li, Xiao-Ming 1; Gloer, James B.2; Wang, Bin-Gui1
	2011-09-28
发表期刊	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN	0021-8561
卷号	59 期号:18 页码:9916-9921
文章类型	Article
摘要	A total of 19 naturally occurring bromophenols, with six new and 13 known structures, were isolated and identified from the methanolic extract of the marine red alga Rhodomela confervoides. The new compounds were identified by spectroscopic methods as 3,4-dibromo-5-((methylsulfonyl)methyl)benzene-1,2-diol (1), 3,4-dibromo-5-((2,3-dihydroxypropoxy)methyl)benzene-1,2-diol (2), 5-(aminomethyl)-3,4-dibromobenzene-1,2-diol (3), 2-(2,3-dibromo-4,5-dihydroxyphenyl)acetic acid (4), 2-methoxy-3-bromo-5-hydroxymethylphenol (5), and (E)-4-(2-bromo-4,5-dihydroxyphenyl)but-3-en-2-one (6). Each compound was evaluated for free radical scavenging activity against DPPH (a,alpha-diphenyl-beta-dipicrylhydrazyl) and ABTS [2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt] radicals. Most of them exhibited potent activities stronger than or comparable to the positive controls butylated hydroxytoluene (BHT) and ascorbic acid. The results from this study suggest that R. confervoides is an excellent source of natural antioxidants, and inclusion of these antioxidant-rich algal components would likely help prevent the oxidative deterioration of food.; A total of 19 naturally occurring bromophenols, with six new and 13 known structures, were isolated and identified from the methanolic extract of the marine red alga Rhodomela confervoides. The new compounds were identified by spectroscopic methods as 3,4-dibromo-5-((methylsulfonyl)methyl)benzene-1,2-diol (1), 3,4-dibromo-5-((2,3-dihydroxypropoxy)methyl)benzene-1,2-diol (2), 5-(aminomethyl)-3,4-dibromobenzene-1,2-diol (3), 2-(2,3-dibromo-4,5-dihydroxyphenyl)acetic acid (4), 2-methoxy-3-bromo-5-hydroxymethylphenol (5), and (E)-4-(2-bromo-4,5-dihydroxyphenyl)but-3-en-2-one (6). Each compound was evaluated for free radical scavenging activity against DPPH (a,alpha-diphenyl-beta-dipicrylhydrazyl) and ABTS [2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt] radicals. Most of them exhibited potent activities stronger than or comparable to the positive controls butylated hydroxytoluene (BHT) and ascorbic acid. The results from this study suggest that R. confervoides is an excellent source of natural antioxidants, and inclusion of these antioxidant-rich algal components would likely help prevent the oxidative deterioration of food.
关键词	Marine Alga Rhodomela Confervoides Bromophenol Radical Scavenging Activity Dpph Abts
学科领域	Agriculture ; Chemistry ; Food Science & Technology
DOI	10.1021/jf2022447
URL	查看原文
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000295059100024
引用统计	被引频次：46[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/11887
专题	实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Iowa, Dept Chem, Iowa City, IA 52242 USA
第一作者单位	实验海洋生物学重点实验室
推荐引用方式 GB/T 7714	Li, Ke,Li, Xiao-Ming,Gloer, James B.,et al. Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2011,59(18):9916-9921.
APA	Li, Ke,Li, Xiao-Ming,Gloer, James B.,&Wang, Bin-Gui.(2011).Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,59(18),9916-9921.
MLA	Li, Ke,et al."Isolation, Characterization, and Antioxidant Activity of Bromophenols of the Marine Red Alga Rhodomela confervoides".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 59.18(2011):9916-9921.

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