Discover of a Novel SNP Highly Associated with Chicken Blue Egg

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	Discover of a Novel SNP Highly Associated with Chicken Blue Egg
	Wang, Z. P.1; Wang, X. T.2; Liu, R. F.3; Wang, A. R.4; Li, J. Y.1; Deng, X. M.1
	2011
发表期刊	JOURNAL OF ANIMAL AND VETERINARY ADVANCES
ISSN	1680-5593
卷号	10 期号:1 页码:92-95
文章类型	Article
摘要	Blue egg is caused by a dominant mutation, Oocyan (O) which is previous located on short arm of chicken chromosome 1 but precise genetic mechanism underlying blue egg is still unknown so far. In this study, we found a SNP (g.67419892-67419904del13) significantly associated with blue egg using 126 browned-shelled chickens and 202 blue-shelled chickens. The allelic and genotypic frequencies of g.67419892-67419904del13 are significantly higher in blue-shelled chickens (92.5 and 87.1%) compared with brown-shelled chickens (10.7 and 8.7%, p < 0.0001). Moreover, the genetic distance between O and g.67419892-67419904del13 is estimated to be over 2 cM (LOD = 13.51) using 149 F(2) offspring from mating between blue-shelled males and brown-shelled females. Apparently, the marker is useful for the cloning of O and marker aid selection of blue-shelled chicken breed.; Blue egg is caused by a dominant mutation, Oocyan (O) which is previous located on short arm of chicken chromosome 1 but precise genetic mechanism underlying blue egg is still unknown so far. In this study, we found a SNP (g.67419892-67419904del13) significantly associated with blue egg using 126 browned-shelled chickens and 202 blue-shelled chickens. The allelic and genotypic frequencies of g.67419892-67419904del13 are significantly higher in blue-shelled chickens (92.5 and 87.1%) compared with brown-shelled chickens (10.7 and 8.7%, p < 0.0001). Moreover, the genetic distance between O and g.67419892-67419904del13 is estimated to be over 2 cM (LOD = 13.51) using 149 F(2) offspring from mating between blue-shelled males and brown-shelled females. Apparently, the marker is useful for the cloning of O and marker aid selection of blue-shelled chicken breed.
关键词	Chicken Blue Egg Snp Association Linkage Chromosome
学科领域	Veterinary Sciences
收录类别	SCI
语种	英语
WOS记录号	WOS:000286530500018
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/11841
专题	实验海洋生物学重点实验室
作者单位	1.China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Inner Mongolia Agr Univ, Vocat & Tech Coll, Baotou 014109, Peoples R China 4.DaBeiNong Grp, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Wang, Z. P.,Wang, X. T.,Liu, R. F.,et al. Discover of a Novel SNP Highly Associated with Chicken Blue Egg[J]. JOURNAL OF ANIMAL AND VETERINARY ADVANCES,2011,10(1):92-95.
APA	Wang, Z. P.,Wang, X. T.,Liu, R. F.,Wang, A. R.,Li, J. Y.,&Deng, X. M..(2011).Discover of a Novel SNP Highly Associated with Chicken Blue Egg.JOURNAL OF ANIMAL AND VETERINARY ADVANCES,10(1),92-95.
MLA	Wang, Z. P.,et al."Discover of a Novel SNP Highly Associated with Chicken Blue Egg".JOURNAL OF ANIMAL AND VETERINARY ADVANCES 10.1(2011):92-95.

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