Antitumor Peptides from Marine Organisms

doi:10.3390/md9101840

IOCAS-IR > 实验海洋生物学重点实验室

	Antitumor Peptides from Marine Organisms
	Zheng, Lan-Hong 3; Wang, Yue-Jun 3; Sheng, Jun 3; Wang, Fang 3; Zheng, Yuan 3; Lin, Xiu-Kun 1,2; Sun, Mi 3
	2011-10-01
发表期刊	MARINE DRUGS
ISSN	1660-3397
卷号	9 期号:10 页码:1840-1859
文章类型	Review
摘要	The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.; The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new antitumor agents in the field of the development of marine bioactive substances. In this review, the progress on studies of antitumor peptides from marine sources is provided. The biological properties and mechanisms of action of different marine peptides are described; information about their molecular diversity is also presented. Novel peptides that induce apoptosis signal pathway, affect the tubulin-microtubule equilibrium and inhibit angiogenesis are presented in association with their pharmacological properties. It is intended to provide useful information for further research in the fields of marine antitumor peptides.
关键词	Antitumor Peptides Marine Organisms
学科领域	Pharmacology & Pharmacy
DOI	10.3390/md9101840
URL	查看原文
收录类别	SCI
语种	英语
WOS记录号	WOS:000298928300008
引用统计	被引频次：120[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qdio.ac.cn/handle/337002/11783
专题	实验海洋生物学重点实验室
作者单位	1.Capital Med Univ, Dept Pharmacol, Beijing 100069, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Chinese Acad Fishery Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Zheng, Lan-Hong,Wang, Yue-Jun,Sheng, Jun,et al. Antitumor Peptides from Marine Organisms[J]. MARINE DRUGS,2011,9(10):1840-1859.
APA	Zheng, Lan-Hong.,Wang, Yue-Jun.,Sheng, Jun.,Wang, Fang.,Zheng, Yuan.,...&Sun, Mi.(2011).Antitumor Peptides from Marine Organisms.MARINE DRUGS,9(10),1840-1859.
MLA	Zheng, Lan-Hong,et al."Antitumor Peptides from Marine Organisms".MARINE DRUGS 9.10(2011):1840-1859.

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