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| A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities | |
| Zhang, Hongyu1,2; Wang, Hongpeng3; Cui, Hongli1; Li, Zonggang4; Xie, Zeping1; Pu, Yang1; Li, Fuchao5; Qin, Song1 | |
| 2011-09-01 | |
| 发表期刊 | MARINE DRUGS
 |
| ISSN | 1660-3397 |
| 卷号 | 9期号:9页码:1502-1509 |
| 文章类型 | Article |
| 摘要 | A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549.; A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549. |
| 关键词 | Streptomyces Anthracene Structure Establishment Cytotoxicity |
| 学科领域 | Pharmacology & Pharmacy |
| DOI | 10.3390/md9091502 |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000298927500005 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qdio.ac.cn/handle/337002/11753 |
| 专题 | 实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany 4.China Agr Univ, Yantai Inst China Agr Univ, Yantai 264670, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hongyu,Wang, Hongpeng,Cui, Hongli,et al. A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities[J]. MARINE DRUGS,2011,9(9):1502-1509. |
| APA | Zhang, Hongyu.,Wang, Hongpeng.,Cui, Hongli.,Li, Zonggang.,Xie, Zeping.,...&Qin, Song.(2011).A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities.MARINE DRUGS,9(9),1502-1509. |
| MLA | Zhang, Hongyu,et al."A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities".MARINE DRUGS 9.9(2011):1502-1509. |
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